1,3-Dimercaptopropane CAS#109-80-8
1,3-Dimercaptopropane is normally presented as a colorless, transparent liquid under room temperature conditions. As it is sensitive to oxidation and other external environmental influences, it may gradually take on a subtle pale yellow hue after prolonged storage.
At normal temperature and standard atmospheric pressure, it stays in a free-flowing liquid state with great handling convenience. Its density is a little higher than water, and it only dissolves sparingly in water. It mixes completely and uniformly with nearly all mainstream organic solvents, including ethanol, ether, benzene, chloroform and other similar solvent categories.
1,3-Dimercaptopropane Chemical Properties
| Product Name: | 1,3-Dimercaptopropane |
| Synonyms: | 1,3-Propanedimercaptan;1,3-propyldimercaptan;NDR-132;FEMA 3588;DITHIOTRIMETHYLENEGLYCOL;1,3-DIMERCAPTOPROPANE;1,3-PROPANEDITHIOL;propane-1,3-dithiol |
| CAS: | 109-80-8 |
| MF: | C3H8S2 |
| MW: | 108.23 |
| EINECS: | 203-706-9 |
| Product Categories: | Building Blocks;Chemical Synthesis;Contact Printing;Dithiols;Materials Science;Micro/NanoElectronics;thiol Flavor;Organic Building Blocks;Self Assembly &;Self-Assembly Materials;Sulfur Compounds;Thiols;Thiols/Mercaptans |
| Mol File: | 109-80-8.mol |
| Melting point | -79 °C (lit.) |
| Boiling point | 169 °C (lit.) |
| density | 1.078 g/mL at 25 °C (lit.) |
| vapor density | >1 (vs air) |
| vapor pressure | 5 mm Hg ( 37.7 °C) |
| refractive index | n20/D 1.539(lit.) |
| FEMA | 3588 | 1,3-PROPANEDITHIOL |
| Fp | 138 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| pka | 9.86±0.10(Predicted) |
| color | Clear light yellow |
| Specific Gravity | 1.078 |
| Odor | at 0.10 % in propylene glycol. meaty sulfurous |
| Odor Type | meaty |
| biological source | synthetic |
| Water Solubility | <0.1 g/100 mL at 21 ºC |
| JECFA Number | 535 |
| Merck | 147801 |
| BRN | 1071197 |
| Stability: | Stable. Incompatible with oxidizing agents, bases, reducing agents, alkali metals. Store cool. |
| LogP | 1.7 |
| CAS DataBase Reference | 109-80-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Propanedithiol(109-80-8) |
| EPA Substance Registry System | 1,3-Propanedithiol (109-80-8) |
Product Usage
1,3-Propanedithiol is a highly versatile chemical reagent that sees massive use in the synthesis of thioketals and thioacetals. It doubles as a functional flavoring agent, and acts as a core foundational material to produce cyclic dithioacetal derivatives known as 1,3-dithianes by reacting with different carbonyl compounds.
It can react smoothly with triiron dodecacarbonyl to synthesize diiron propanedithiolate hexacarbonyl. On top of that, 1,3-propanedithiol is a go-to choice for protecting aldehyde and ketone functional groups: it forms reversible dithiane structures that temporarily block these groups during complex synthesis workflows. It also binds with metal ions to create highly stable chelate rings, making it an incredibly useful material for coordination chemistry and all related application scenarios.
