5-Methoxy-2-tetralone CAS#32940-15-1

As a High-Value Pharmaceutical Intermediate‌: It finds widespread application in pharmaceutical research and development, most notably in the synthesis of sertraline analogues and other compounds associated with neurotransmitters.

‌Offering Versatile Chemical Reactivity‌: The molecule's substituted tetralone core facilitates a range of functional modifications, thereby supporting extensive synthetic applications.

Exhibiting Reliable Physicochemical Properties‌: It boasts a stable molecular structure (C₁₁H₁₂O₂) and a well-defined melting point range (32–36 °C), which ensures consistent and predictable behavior in laboratory procedures.

Featuring a Distinct Physical Form for Easy Handling‌: The compound presents as a yellow to orange solid, which simplifies visual identification and ensures convenient manipulation during manufacturing and research operations.

Product Details
Chemical Properties
Product Application

Products Description of 5-Methoxy-2-Tetralone CAS#32940-15-1

5-Methoxy-2-tetralone (CAS 32940-15-1) is a substituted tetralone compound extensively employed as an intermediate in pharmaceutical research, notably in the synthesis of sertraline analogs and other compounds related to neurotransmitters. This organic compound possesses the molecular formula C₁₁H₁₂O₂ and typically presents as a yellow to orange solid, with a documented melting point in the range of 32–36 °C.

5-Methoxy-2-tetralone CAS#32940-15-1

5-Methoxy-2-tetralone Chemical Properties

Melting point 32-36 °C (lit.)
Boiling point 165°C/10mmHg(lit.)
density 1.124±0.06 g/cm3(Predicted)
vapor pressure 0.059Pa at 25℃
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane, Ethyl Acetate, Methanol
form Solid
color Yellowish Orange
BRN 1451623
InChIKeyMDAIAXRTLTVEOU-UHFFFAOYSA-N
LogP1.8 at 25℃
CAS DataBase Reference32940-15-1(CAS DataBase Reference)
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29145090

Product Application

5-Methoxy-2-tetralone is a core building block in the synthesis of a variety of bioactive molecules:

Pharmaceutical Synthesis‌: It serves as a key intermediate in the synthesis of rotigotine, a dopamine receptor agonist employed in the treatment of Parkinson's disease and restless legs syndrome.

Research and Development Applications‌: It is widely utilized in laboratory-scale synthetic research as a starting material for constructing polycyclic aromatic hydrocarbons and functionalized naphthalene derivatives.

5-Methoxy-2-tetralone CAS#32940-15-1